1: ethyl (3R)-1-[(Z)-4-iodo-4-(3-methyl-2-thienyl)-3-butenyl]hexahydro-3-pyridinecarboxylate With tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water T=20°C; Suzuki coupling; 0.25 h; Inert atmosphere; 2: 6-(3-methylthiophen-2-yl)boronic acid in ethylene glycol dimethyl ether; ethanol; water T=90°C; Suzuki coupling; Inert atmosphere;