1: 4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzoic acid methyl ester With hydroxylamine hydrochloride; sodium methylate in methanol T=20°C; 24 h; Inert atmosphere; 2: trifluoroacetic acid in water HPLC column;
参考文献
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; KOZIKOWSKI, Alan; BUTLER, Kyle, B.; KALIN, Jay, Hans
Patent: WO2011/11186 A2, 2011 ;
Location in patent: Page/Page column 54-55 ;
WO 2011/011186 A2
Butler, Kyle V.; Kalin, Jay; Brochier, Camille; Vistoli, Guilio; Langley, Brett; Kozikowski, Alan P.
Journal of the American Chemical Society, 2010 , vol. 132, # 31 p. 10842 - 10846
