5-[[3-溴-4-(2-环己基乙氧基)苯基]亚甲基]-2,4-噻唑烷二酮合成路线 (共 2 条)
反应条件
piperidine; acetic acid in toluene Knoevenagel condensation; 12 h; Reflux;
参考文献
Wu, Ying; Karna, Sandeep; Choi, Cheol Hee; Tong, Min; Tai, Hsin-Hsiung; Na, Dong Hee; Jang, Chul Ho; Cho, Hoon
Journal of Medicinal Chemistry, 2011 , vol. 54, # 14 p. 5260 - 5264
反应条件
1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 18 h / 25 °C 2: piperidine; acetic acid / toluene / 12 h / Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 14 p. 5260 - 5264