1: potassium hydroxide / water / 6 h / 60 °C 2: N,N-dimethyl-aniline / 1,4-dioxane / 3 h / 60 °C View Scheme

1: potassium hydroxide / water / 6 h / 60 °C 2: N,N-dimethyl-aniline / 1,4-dioxane / 3 h / 60 °C 3: dicyclohexyl-carbodiimide; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 48 h View Scheme

potassium hydroxide in water T=60°C; 6 h;