1: 2-(Diethoxy-phosphoryl)-propionic acid ethyl ester With sodium hydride in tetrahydrofuran
T=20°C; 1.5 h;
2: Caprylic Aldehyde in tetrahydrofuran
Title compound not separated from byproducts;
chloro-trimethyl-silane in tetrahydrofuran
-78 deg C, 3 h, then room t., 16 h; reactions of sev. aldehydes in presence of var. reagents (Lewis acids, TFAA, NCS, MeI, I2) under var. conditions; Product distributionMechanism;
参考文献
Pelter, Andrew; Smith, Keith; Elgendy, Said M. A.; Rowlands, Martin
Tetrahedron, 1993 , vol. 49, # 32 p. 7104 - 7118
