1: sodium trichloroacetate / dimethylformamide / 4 h / 20 °C
2: dimethylformamide / 1 h / 20 °C
3: zinc powder / acetic acid / 1 h / 60 °C
View Scheme
参考文献
Wang, Zhe; Campagna, Silvio; Xu, Guoyou; Pierce, Michael E.; Fortunak, Joseph M.; Confalone, Pat N.
Tetrahedron Letters, 2000 , vol. 41, # 21 p. 4007 - 4009
1: methylthio(tert-butyldimethylsilyl)trimethylsilyl-methane With n-butyllithium in tetrahydrofuran; hexane
T=-78 - 0°C;
2: pelargonaldehyde in tetrahydrofuran; hexane
T=-78 - 20°C; Peterson olefination; 3 h; Title compound not separated from byproducts;
