1: 2,3-dichloropyridine With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78°C; 2 h; 2: carbon dioxide in tetrahydrofuran; hexane 1 h; 3: With hydrogenchloride in tetrahydrofuran; hexane; water pH=1;
参考文献
MITSUBISHI PHARMA CORPORATION; SANOFI-AVENTIS
Patent: WO2006/36015 A2, 2006 ;
Location in patent: Page/Page column 123 ;
WO 2006/036015 A2