1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
Heating;
参考文献
Hooker, Jacob M.; Schueller, Michael J.; Fowler, Joanna S.; Reibel, Achim T.; Hill, Sidney M.
Angewandte Chemie, International Edition, 2009 , vol. 48, # 19 p. 3482 - 3485
1: 4-pyrrolylchlorobenzene With 2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran
T=-75°C; 1 h;
2: carbon dioxide in tetrahydrofuran; diethyl ether
T=20°C; Further stages.;
参考文献
Fogassy, Katalin; Kovacs, Krisztina; Keseru, Gyoergy M.; Toke, Laszlo; Faigl, Ferenc
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1039 - 1043
1: 4-pyrrolylchlorobenzene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran
T=-75°C; 1 h;
2: carbon dioxide in tetrahydrofuran; diethyl ether
T=20°C; Further stages. Title compound not separated from byproducts.;
参考文献
Fogassy, Katalin; Kovacs, Krisztina; Keseru, Gyoergy M.; Toke, Laszlo; Faigl, Ferenc
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1039 - 1043
1: 1-(iodo)-4-methylbenzene; cyclohexylamine With sodium carbonate in water
0.166667 h; Autoclave;
2: carbon dioxide in water
T=100°C; P=5171.62 Torr; 8 h; Autoclave;
1: C7H2Br3N With isopropylmagnesium chloride in tetrahydrofuran
T=-40°C; Grignard reaction; 2 h;
2: carbon dioxide in tetrahydrofuran
T=-40°C; 1 h; Further stages. Title compound not separated from byproducts.;
参考文献
Menzel, Karsten; Mills, Paul M.; Frantz, Doug E.; Nelson, Todd D.; Kress, Michael H.
Tetrahedron Letters, 2008 , vol. 49, # 3 p. 415 - 418
