2-氨基-2-甲基-1-丙醇合成路线 （共 271 条）
反应条件
(i), (ii) (heating); Multistep reaction;
参考文献
Lion,C.; Dubois,J.E.
Tetrahedron, 1973 , vol. 29, p. 3417 - 3423
反应条件
zinc(II) chloride in chlorobenzene 24 h; Reflux;
参考文献
Sedelmeier, Joerg; Hammerer, Tim; Bolm, Carsten
Organic Letters, 2008 , vol. 10, # 5 p. 917 - 920
反应条件
T=170°C; 0.25 h; Microwave irradiationNeat (no solvent)open vessel;
参考文献
Sharma, Rishi; Vadivel, Subramanian K.; Duclos Jr., Richard I.; Makriyannis, Alexandros
Tetrahedron Letters, 2009 , vol. 50, # 42 p. 5780 - 5782
反应条件
potassium tert-butylate in dichloromethane
参考文献
Lee, Chun-Ho; Khoo, Ja-Heouk; Kwon, Kyoung-Chan; Ju, Hyun
Patent: US2011/9636 A1, 2011 ;
Location in patent: Page/Page column 6 ;
反应条件
in dichloromethane T=20°C; 24 h;
参考文献
Houlihan, William J.; Boja, John W.; Kopajtic, Theresa A.; Kuhar, Michael J.; Degrado, Sylvia J.; Toledo, Leonel
Medicinal Chemistry Research, 1998 , vol. 8, # 1-2 p. 77 - 90
反应条件
1: 4-bromophenylacetic acid With pyridine; 2,4,6-trichloro-1,3,5-triazine in dichloromethane T=0°C; 0.25 h; 2: 2-amino-2-methyl-propan-1-ol With indium in dichloromethane T=20°C; 20 h;
参考文献
Kangani, Cyrous O.; Day, Billy W.
Tetrahedron Letters, 2009 , vol. 50, # 38 p. 5332 - 5335
反应条件
thionyl chloride; triethylamine in dichloromethane; toluene
参考文献
Otsuka Pharmaceutical Company, Limited
Patent: US6096735 A1, 2000 ;
反应条件
1: With triethylamine in dichloromethane T=0 - 20°C; 5 h; 2: With thionyl chloride in dichloromethane T=0 - 20°C; 3 h;
参考文献
Otsuka Pharmaceuticals Co., Ltd.
Patent: US6335327 B1, 2002 ;
Location in patent: Page column 84 ;
反应条件
zinc(II) chloride 15 h; Irradiation;
参考文献
Clarke, David S.; Wood, Robin
Synthetic Communications, 1996 , vol. 26, # 7 p. 1335 - 1340
反应条件
[bis(2-methoxyethyl)amino]-sulfur trifluoride in dichloromethane T=0°C; 0.5 h;
参考文献
Kangani, Cyrous O.; Kelley, David E.
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8917 - 8920
