2-氨基-2-甲基-1-丙醇合成路线 （共 271 条）
反应条件
1: 2-amino-2-methyl-propan-1-ol With n-butyllithium in dichloromethane T=0°C; Metallation; after the reagent addition stirring for 15 min at this temperature under nitrogen, then warming to reflux; 2: ethyl 4-acetyl-5-methyl-1,2-oxazole-3-carboxylate Hydrolysis; 12 h; reflux;
参考文献
Zhou, Peiwen; Natale
Synthetic Communications, 1998 , vol. 28, # 18 p. 3317 - 3330
参考文献
Feuer, Henry; Bevinakatti, Hanamanthsa S.; Luo, Xuan-Gan
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 825 - 832
反应条件
1: in chloroform T=80°C; P=206.859 - 517.148 Torr; 0.166667 h; microwave irradiation; 2: With thionyl chloride in chloroform T=80°C; 0.0333333 h; microwave irradiation;
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
zinc(II) chloride in chlorobenzene 48 h; Inert atmosphereReflux;
参考文献
Bellamy, Estelle; Bayh, Omar; Hoarau, Christophe; Trecourt, Francois; Queguiner, Guy; Marsais, Francis
Chemical Communications, 2010 , vol. 46, # 37 p. 7043 - 7045
反应条件
1: 2-chloro-5-carboxybenzene With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-[1,3,5]triazine in dichloromethane 2: 2-amino-2-methyl-propan-1-ol in dichloromethane T=20°C; 6 h;
参考文献
Bandgar; Pandit
Tetrahedron Letters, 2003 , vol. 44, # 11 p. 2331 - 2333
反应条件
Erhitzen des Reaktionsprodukts in 1-Nitro-propan auf 125grad;
参考文献
Smith, Kline and French Labor.
Patent: US2463831 , 1946 ;
参考文献
Kremer; Kress
Journal of the American Chemical Society, 1938 , vol. 60, p. 1031
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Kremer
Journal of the American Chemical Society, 1937 , vol. 59, p. 1681
Journal of the American Chemical Society, 1939 , vol. 61, p. 1321,1323
反应条件
Zn4(OCOCF3)6O in chlorobenzene 12 h; Heating;
参考文献
Takasago International Corporation
Patent: EP1958940 A1, 2008 ;
Location in patent: Page/Page column 24-25 ;
反应条件
Zn4(OCOCF3)6O in chlorobenzene 18 h; Heating;
参考文献
Takasago International Corporation
Patent: EP1958940 A1, 2008 ;
Location in patent: Page/Page column 24-25 ;
反应条件
ytterbium(III) triflate in 1,2-dichloro-benzene T=170°C; 24 h;
参考文献
Berg, David J.; Zhou, Chuanjian; Barclay, Tosha; Fei, Xuening; Feng, Shengyu; Ogilvie, Kevin A.; Gossage, Robert A.; Twamley, Brendan; Wood, Mark
Canadian Journal of Chemistry, 2005 , vol. 83, # 5 p. 449 - 459
