2-氨基-2-甲基-1-丙醇合成路线 (共 271 条)
参考文献
Shono, Tatsuya; Kashimura, Shigenori; Yamaguchi, Yoshihide; Ishige, Osamu; Uyama, Hiroshi; Kuwata, Fumitaka
Chemistry Letters, 1987 , p. 1511 - 1512
反应条件
triethylamine in tetrahydrofuran 1.) 20 deg C, 2.) 65 deg C, 2 h;
参考文献
Courtois, G.; Miginiac, L.
Journal of Organometallic Chemistry, 1988 , vol. 340, p. 127 - 142
参考文献
Courtois, G.; Miginiac, L.
Journal of Organometallic Chemistry, 1993 , vol. 450, # 1.2 p. 33 - 40
反应条件
1: 2-amino-2-methyl-propan-1-ol With sulfuric acid; sulfur trioxide
T=85 - 90°C;
2: With sodium hydroxide in water
T=30°C;
3: sodium thiomethoxide in water
T=30 - 65°C; 6 h;
参考文献
BAYER CROPSCIENCE AG
Patent: WO2007/22901 A1, 2007 ;
Location in patent: Page/Page column 18-19 ;
参考文献
SOSEI R and D LTD.
Patent: WO2007/3896 A1, 2007 ;
Location in patent: Page/Page column 8 ;
反应条件
sodium hydroxide; thionyl chloride in hexane; dichloromethane; water; toluene
参考文献
Shionogi and Co., Ltd.
Patent: US5488134 A1, 1996 ;
参考文献
Billman; Koehler; May
Journal of pharmaceutical sciences, 1969 , vol. 58, # 6 p. 767 - 769
反应条件
(i) SOCl2, (ii) /BRN= 505979/, CH2Cl2, (iii) SOCl2; Multistep reaction;
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1372 - 1379
参考文献
Combret,J.-C.; Tekin,J.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1977 , vol. 285, p. 249 - 251
反应条件
zinc(II) chloride
15 h; Irradiation;
参考文献
Clarke, David S.; Wood, Robin
Synthetic Communications, 1996 , vol. 26, # 7 p. 1335 - 1340