2-氨基-2-甲基-1-丙醇合成路线 (共 271 条)
反应条件
sodium sulfate; trifluoroacetic acid
参考文献
Bayer Corporation
Patent: US6353006 B1, 2002 ;
Location in patent: Page column 50-51 ;
US 6353006 B1
反应条件
in diethyl ether
T=15 - 20°C; 2 h;
参考文献
Gryaznov; Kataeva; Naumova; Musin; Al'fonsov
Russian Journal of General Chemistry, 2010 , vol. 80, # 4 p. 761 - 764
反应条件
in dichloromethane
12 h; Ambient temperature;
参考文献
Muller; Retzow; Wiegrebe
Archiv der Pharmazie, 1984 , vol. 317, # 2 p. 120 - 126
参考文献
Denny, William Alexander; Hutchings, Richard H; Johnson, Douglas S; Kaltenbronn, James Stanely; Lee, Ho Huat; Leonard, Daniele Marie; Milbank, Jared Bruce John; Repine, Joseph Thomas; Rewcastle, Gordon William; White, Andrew David
Patent: US2004/44057 A1, 2004 ;
反应条件
1:
2: With oxalyl dichloride
Swern Oxidation;
参考文献
NEUROCRINE BIOSCIENCES, INC.
Patent: WO2005/7633 A1, 2005 ;
Location in patent: Page 29 ;
WO 2005/007633 A1
参考文献
Meyers,A.I.; Williams,B.E.
Tetrahedron Letters, 1978 , p. 223 - 226
参考文献
Monsanto Company
Patent: US5498630 A1, 1996 ;
参考文献
Meyers,A.I.; Williams,B.E.
Tetrahedron Letters, 1978 , p. 223 - 226
参考文献
VanderWerf et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 1231,1233
反应条件
in chloroform
T=80°C; 168 h;
参考文献
Nishiwaki, Nagatoshi; Nishida, Daisei; Ohnishi, Tetsuya; Hidaka, Fumie; Shimizu, Satoru; Tamura, Mina; Hori, Kazushige; Tohda, Yasuo; Ariga, Masahiro
Journal of Organic Chemistry, 2003 , vol. 68, # 22 p. 8650 - 8656