2-氨基-2-甲基-1-丙醇合成路线 （共 271 条）
反应条件
thionyl chloride; oxalyl dichloride; triethylamine
1.) CH2Cl2, DMF, room temperature, 5 h, 2.) CH2Cl2, room temperature, overnight, 3.) CH2Cl2, room temperature, 4 h; Yield given. Multistep reaction;
参考文献
Shimano, Masanao; Matsuo, Atsushi
Tetrahedron, 1998 , vol. 54, # 19 p. 4787 - 4810
反应条件
1: (+/-)-2-Phenylpropionic acid With pyridine; 2,4,6-trichloro-1,3,5-triazine in dichloromethane
T=0°C; 0.25 h;
2: 2-amino-2-methyl-propan-1-ol With indium in dichloromethane
T=20°C; 30 h;
参考文献
Kangani, Cyrous O.; Day, Billy W.
Tetrahedron Letters, 2009 , vol. 50, # 38 p. 5332 - 5335
反应条件
water
T=400°C; 0.2 h; other temperature; Product distributionMechanism;
参考文献
Feron, Damien; Lambert, Irma
Journal of Solution Chemistry, 1992 , vol. 21, # 8 p. 919 - 932
参考文献
Mallory, Frank B.; Butler, Kelly E.; Evans, Amanda C.; Brondyke, Emilie J.; Mallory, Clelia W.; Yang, Changqing; Ellenstein, Aviva
Journal of the American Chemical Society, 1997 , vol. 119, # 9 p. 2119 - 2124
反应条件
1: in chloroform
T=80°C; P=206.859 - 517.148 Torr; 0.166667 h; microwave irradiation;
2: With thionyl chloride in chloroform
T=80°C; 0.0333333 h; microwave irradiation;
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
[bis(2-methoxyethyl)amino]-sulfur trifluoride in dichloromethane
T=0°C; 0.5 h;
参考文献
Kangani, Cyrous O.; Kelley, David E.
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8917 - 8920
反应条件
Kaolinitic clay
T=165°C; 24 h;
参考文献
Jnaneshwara; Deshpande; Lalithambika; Ravindranathan; Bedekar
Tetrahedron Letters, 1998 , vol. 39, # 5-6 p. 459 - 462
反应条件
in chloroform
T=25°C; 12 h;
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
triethylamine in diethyl ether
参考文献
Cates; Li; Yakshe; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 654 - 659
反应条件
thionyl chloride
Yield given. Multistep reaction;
参考文献
Novak, Jiri; Salemink, Cornelis A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2867 - 2871
