2-氨基-2-甲基-1-丙醇合成路线 （共 271 条）
反应条件
in 1,4-dioxane
1.) 10 deg C, 1 h; 2.) room temp., 2 h;
参考文献
Yamada; Niino; Hashimoto; Shuto; Nakamizo; Kubo; Ono; Murayama
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1214 - 1220
反应条件
TEA
1.) CH2Cl2, 1 h, 2.) 120 deg C, 1.5 h; Yield given. Multistep reaction;
参考文献
Diana; McKinlay; Otto; Akullian; Oglesby
Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1906 - 1910
反应条件
1: in chloroform
T=80°C; P=206.859 - 517.148 Torr; 0.166667 h; microwave irradiation;
2: With thionyl chloride in chloroform
T=80°C; 0.0333333 h; microwave irradiation;
参考文献
Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K.
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814
反应条件
1: salicylic acid With pyridine; 2,4,6-trichloro-1,3,5-triazine in dichloromethane
T=0°C; 0.25 h;
2: 2-amino-2-methyl-propan-1-ol With indium in dichloromethane
T=20°C; 30 h;
参考文献
Kangani, Cyrous O.; Day, Billy W.
Tetrahedron Letters, 2009 , vol. 50, # 38 p. 5332 - 5335
反应条件
in methanol
1 h; Reflux;
参考文献
Rezaeifard, Abdolreza; Jafarpour, Maasoumeh; Raissi, Heidar; Alipour, Mahboubeh; Stoeckli-Evans, Helen
Zeitschrift fur Anorganische und Allgemeine Chemie, 2012 , vol. 638, # 6 p. 1023 - 1030
反应条件
(6-(di-tert-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine)Ru(H)(CO) in 1,4-dioxane
T=135°C; 19 h; Inert atmosphere;
参考文献
Gnanaprakasam, Boopathy; Balaraman, Ekambaram; Ben-David, Yehoshoa; Milstein, David
Angewandte Chemie - International Edition, 2011 , vol. 50, # 51 p. 12240 - 12244
参考文献
Rajadhyaksha; Vithal J.
Patent: US5030629 A1, 1991 ;
反应条件
potassium hydroxide
1.) 150 deg C; 2.) 180 deg C; Multistep reaction;
参考文献
Serota, S.; Simon, J. R.; Murray, E. B.; Linfield, W. M.
Journal of Organic Chemistry, 1981 , vol. 46, # 21 p. 4147 - 4151
反应条件
Lawesson's reagent
T=150°C; 0.0666667 h; microwave irradiation;
参考文献
Seijas, Julio A.; Vazquez-Tato, M. Pilar; Crecente-Campo, Jose
Tetrahedron, 2008 , vol. 64, # 39 p. 9280 - 9285
参考文献
Koch,T.H. et al.
Journal of Organic Chemistry, 1975 , vol. 40, p. 14 - 19
