2,4-二氯嘧啶-5-羧酰胺合成路线 (共 2 条)
反应条件
ammonium hydroxide in dichloromethane; water T=-20 - -15°C; Product distribution / selectivity;
参考文献
Singh, Rajinder; Tso, Kin; Zhang, Jing; Duncton, Matthew; Alvarez, Salvador; Kolluri, Rao; Ramphal, John; Holland, Sacha
Patent: US2011/130415 A1, 2011 ;
Location in patent: Page/Page column 41 ;
反应条件
1: With trichlorophosphate T=100°C; 4 h; 2: With ammonium hydroxide in water
参考文献
WO2010/129802 A1, ;
Page/Page column 125 ;
WO 2010/129802 A1