1.1: diisobutylaluminium hydride / dichloromethane; hexane / 0.5 h / -30 °C / Inert atmosphere 1.2: -30 °C 2.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere 2.2: 3.25 h / 0 - 20 °C 3.1: hydrogenchloride / water; tetrahydrofuran / 18 h / 20 °C 3.2: pH 6.8 / Aqueous phosphate buffer View Scheme

1.1: diisobutylaluminium hydride / toluene / -40 °C / Inert atmosphere 1.2: 20 °C 2.1: tetrahydrofuran / -15 - -5 °C / Inert atmosphere 2.2: 15 - 30 °C View Scheme