1.1: NaH / tetrahydrofuran / 1 h / 0 °C 1.2: 80 percent / tetrabutylammonium iodide / tetrahydrofuran / 2 h / 20 °C 2.1: 82 percent / CSA / cyclohexane; CH2Cl2 / 24 h / 20 °C 3.1: 80 percent / DDQ / CH2Cl2; H2O / 1 h / 20 °C 4.1: 65 percent / DMP / CH2Cl2 / 0 - 20 °C 5.1: NaHMDS; HMPA / tetrahydrofuran / 1 h / -30 °C 5.2: 38 percent / tetrahydrofuran / -30 - 20 °C 6.1: 60 percent / Li; liq. NH3 / tetrahydrofuran / 2 h / cooling View Scheme

1.1: NaH / tetrahydrofuran / 1 h / 0 °C 1.2: 80 percent / tetrabutylammonium iodide / tetrahydrofuran / 2 h / 20 °C 2.1: 82 percent / CSA / cyclohexane; CH2Cl2 / 24 h / 20 °C 3.1: 80 percent / DDQ / CH2Cl2; H2O / 1 h / 20 °C 4.1: 65 percent / DMP / CH2Cl2 / 0 - 20 °C 5.1: NaHMDS; HMPA / tetrahydrofuran / 1 h / -30 °C 5.2: 40 percent / tetrahydrofuran / -30 - 20 °C 6.1: 60 percent / Li; liq. NH3 / tetrahydrofuran / 2 h / cooling View Scheme