1241752-29-3合成路线

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; ARONOV, Alex; COME, Jon, H.; DAVIES, Robert, J.; PIERCE, Albert, C.; WANG, Jian; NANTHAKUMAR, Suganthini; CAO, Jingrong; BANDARAGE, Upul, K.; KRUEGER, Elaine; TIRAN, Amaud, Le; LIAO, Yusheng; MESSERSMITH, David; COLLIER, Philip, N.; GREY, Ronald; O'DOWD, Hardwin; HENDERSON, James, A.; GRILLOT, Anne-Laure
Patent: WO2011/87776 A1, 2011 ;
Location in patent: Page/Page column 49; 51 ;
WO 2011/087776 A1

625-92-33,5-二溴吡啶

1241752-29-3

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; ARONOV, Alex; COME, Jon, H.; DAVIES, Robert, J.; PIERCE, Albert, C.; WANG, Jian; NANTHAKUMAR, Suganthini; CAO, Jingrong; BANDARAGE, Upul, K.; KRUEGER, Elaine; TIRAN, Amaud, Le; LIAO, Yusheng; MESSERSMITH, David; COLLIER, Philip, N.; GREY, Ronald; O'DOWD, Hardwin; HENDERSON, James, A.; GRILLOT, Anne-Laure
Patent: WO2011/87776 A1, 2011 ;
WO 2011/087776 A1

17117-17-85-溴-3-乙氧基吡啶

1241752-29-3

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; ARONOV, Alex; COME, Jon, H.; DAVIES, Robert, J.; PIERCE, Albert, C.; WANG, Jian; NANTHAKUMAR, Suganthini; CAO, Jingrong; BANDARAGE, Upul, K.; KRUEGER, Elaine; TIRAN, Amaud, Le; LIAO, Yusheng; MESSERSMITH, David; COLLIER, Philip, N.; GREY, Ronald; O'DOWD, Hardwin; HENDERSON, James, A.; GRILLOT, Anne-Laure
Patent: WO2011/87776 A1, 2011 ;
WO 2011/087776 A1

74115-13-23-溴-5-羟基吡啶

1241752-29-3

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; ARONOV, Alex; COME, Jon, H.; DAVIES, Robert, J.; PIERCE, Albert, C.; WANG, Jian; NANTHAKUMAR, Suganthini; CAO, Jingrong; BANDARAGE, Upul, K.; KRUEGER, Elaine; TIRAN, Amaud, Le; LIAO, Yusheng; MESSERSMITH, David; COLLIER, Philip, N.; GREY, Ronald; O'DOWD, Hardwin; HENDERSON, James, A.; GRILLOT, Anne-Laure
Patent: WO2011/87776 A1, 2011 ;
WO 2011/087776 A1

1241752-29-3+

124-41-4甲醇钠

909854-18-85-溴-3-乙氧基-2-甲氧基吡啶

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; ARONOV, Alex; COME, Jon; COTTRELL, Kevin; GREY, Ronald; LE TIRAN, Amaud; MARONE, Valerie; MARTINEZ-BOTELLA, Gabriel; MESSERSMITH, David; HUCK, Emilie, Porter
Patent: WO2010/135014 A1, 2010 ;
Location in patent: Page/Page column 45-47 ;
WO 2010/135014 A1

67-56-1甲醇+

1241752-29-3+

124-41-4甲醇钠

909854-18-85-溴-3-乙氧基-2-甲氧基吡啶

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; ARONOV, Alex; COME, Jon, H.; DAVIES, Robert, J.; PIERCE, Albert, C.; WANG, Jian; NANTHAKUMAR, Suganthini; CAO, Jingrong; BANDARAGE, Upul, K.; KRUEGER, Elaine; TIRAN, Amaud, Le; LIAO, Yusheng; MESSERSMITH, David; COLLIER, Philip, N.; GREY, Ronald; O'DOWD, Hardwin; HENDERSON, James, A.; GRILLOT, Anne-Laure
Patent: WO2011/87776 A1, 2011 ;
Location in patent: Page/Page column 49; 51 ;
WO 2011/087776 A1