2,2,2-三氟-1-(4-异丙基苯基)乙酮合成路线 (共 3 条)
反应条件
aluminium trichloride in dichloromethane T=0°C; 4 h;
参考文献
Chemistry Letters, , # 5 p. 783 - 786
反应条件
aluminium trichloride in dichloromethane 15 h; Ambient temperature;
参考文献
Synthesis, , # 9 p. 1093 - 1094
反应条件
1: 1-bromo-4-isopropylbenzene With magnesium in tetrahydrofuran Inert atmosphere; 2: 2,2,2-trifluoro-1-pyrrolidin-1-ylethanone in tetrahydrofuran Inert atmosphereReflux;
参考文献
Journal of Medicinal Chemistry, , vol. 53, # 15 p. 5667 - 5675