2-氨基-4-甲基-7-喹啉羧酸合成路线 （共 4 条）
反应条件
ammonia; phenol T=170°C; 16 h;
参考文献
Kelly, T. Ross; Bilodeau, Mark T.; Bridger, Gary J.; Zhao, Chen
Tetrahedron Letters, 1989 , vol. 30, # 19 p. 2485 - 2488
反应条件
1.1: BuLi / tetrahydrofuran / -78 °C 1.2: tetrahydrofuran / -78 °C 2.1: POCl3 / Heating 3.1: NH3 / phenol / 16 h / 170 °C View Scheme
参考文献
Kelly, T. Ross; Bilodeau, Mark T.; Bridger, Gary J.; Zhao, Chen
Tetrahedron Letters, 1989 , vol. 30, # 19 p. 2485 - 2488
反应条件
1.1: H2SO4 2.1: BuLi / tetrahydrofuran / -78 °C 2.2: tetrahydrofuran / -78 °C 3.1: POCl3 / Heating 4.1: NH3 / phenol / 16 h / 170 °C View Scheme
参考文献
Araki, Koji; Tada, Ken-Ichi; Abe, Masanori; Mutai, Toshiki
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 6 p. 1391 - 1396
反应条件
1.1: xylene / Heating 2.1: H2SO4 3.1: BuLi / tetrahydrofuran / -78 °C 3.2: tetrahydrofuran / -78 °C 4.1: POCl3 / Heating 5.1: NH3 / phenol / 16 h / 170 °C View Scheme
参考文献
Araki, Koji; Tada, Ken-Ichi; Abe, Masanori; Mutai, Toshiki
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 6 p. 1391 - 1396
