(3S)-噁烷-3-甲醇合成路线 （共 52 条）
反应条件
hydrogen; Catalyst C prepared in Example C (nickel on mixed silica-zirconia support Zr:Si:Ni 10:28:1) in water T=150°C; P=10336 Torr; 1 - 2 h; Product distribution / selectivity;
参考文献
EASTMAN CHEMICAL COMPANY
Patent: EP1354881 A1, 2003 ;
Location in patent: Page/Page column 6-7 ;
反应条件
[Ru(η4-COD)(η3-methylallyl)2]; 2-(dicyclohexylphosphino)-1-(2-methoxyphenyl)-1H-imidazole; hydrogen in toluene T=160°C; P=37503.8 Torr; 24 h; AutoclaveInert atmosphere; Overall yield = 60 percentChromat.; regioselective reaction;
参考文献
Wu, Lipeng; Fleischer, Ivana; Jackstell, Ralf; Profir, Irina; Franke, Robert; Beller, Matthias
Journal of the American Chemical Society, 2013 , vol. 135, # 38 p. 14306 - 14312
反应条件
[Ru(η4-COD)(η3-methylallyl)2]; 2-(dicyclohexylphosphino)-1-(2-methoxyphenyl)-1H-imidazole; hydrogen in toluene T=160°C; P=37503.8 Torr; 24 h; AutoclaveInert atmosphere; Overall yield = 60 percentChromat.; regioselective reaction;
参考文献
Wu, Lipeng; Fleischer, Ivana; Jackstell, Ralf; Profir, Irina; Franke, Robert; Beller, Matthias
Journal of the American Chemical Society, 2013 , vol. 135, # 38 p. 14306 - 14312
反应条件
amberlyst-15 in methanol T=60 - 120°C;
参考文献
Potluri, Srinagesh Kumar; Ramulu, A. Raghu; Pardhasaradhi
Synthetic Communications, 2005 , vol. 35, # 7 p. 971 - 978
反应条件
isopropyl alcohol T=280 - 330°C; 4 - 6 h;
参考文献
EASTMAN CHEMICAL COMPANY
Patent: EP1431295 A1, 2004 ;
Location in patent: Page 4-5 ;
反应条件
water; hydrogen; copper on zirconia T=150 - 300°C; P=2550.26 - 33603.4 Torr; 6 - 10 h; Product distribution / selectivity;
参考文献
EASTMAN CHEMICAL COMPANY
Patent: EP1431296 A1, 2004 ;
Location in patent: Page 5 ;
反应条件
water; hydrogen; copper on zirconia T=300 - 348°C; P=41372.9 Torr; 3 h; Product distribution / selectivity;
参考文献
EASTMAN CHEMICAL COMPANY
Patent: EP1431296 A1, 2004 ;
Location in patent: Page 9-14 ;
反应条件
1: hydrogen / 5percent Pd/C / ethanol / 288 h / 2 Torr / Ambient temperature 2: LiAlH4 View Scheme
参考文献
Stolze, Rainer; Budzikiewicz, Herbert
Tetrahedron, 1981 , vol. 37, p. 781 - 787
反应条件
1: 98 percent / NaBH4 / methanol / 3 h / 20 °C 2: 90 percent / Amberlyst-15 / methanol / 60 - 120 °C View Scheme
参考文献
Potluri, Srinagesh Kumar; Ramulu, A. Raghu; Pardhasaradhi
Synthetic Communications, 2005 , vol. 35, # 7 p. 971 - 978
反应条件
lithium aluminium tetrahydride
参考文献
Pratesi; Villa; Ferri; et al.
Farmaco, Edizione Scientifica, 1984 , vol. 39, # 3 p. 171 - 188
