反应条件
1: 76 percent / KOH, H2O / ethanol / 48 h / Ambient temperature 2: 1.) 4-methylmorpholine, isobutyl chloroformate / 1.) THF, 5 min, 2.) RT, 5 min View Scheme
参考文献
Kohn, Harold; Sawhney, Kailash N.; LeGall, Philippe; Conley, Judith D.; Robertson, David W.; Leander, J. David
Journal of Medicinal Chemistry, 1990 , vol. 33, # 3 p. 919 - 926
