2-氯-7,8-二氢-6H-喹啉-5-酮合成路线 （共 4 条）
反应条件
trichlorophosphate in acetonitrile T=75°C; 1.25 h; Inert atmosphere;
参考文献
US2014/31391 A1, ;
Paragraph 0368; 0369; 0370 ;
反应条件
1: 170 °C / Neat (no solvent) 2: trichlorophosphate View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 240 - 244
反应条件
1: ammonium acetate / toluene / 2 h / |Reflux 2: 1.92 h / 105 - 170 °C 3: trichlorophosphate / acetonitrile / 1.25 h / 75 °C / |Inert atmosphere View Scheme
反应条件
triethylamine; tetrakis(triphenylphosphine) palladium(0)
3 h; Heating / reflux;
参考文献
MERZ PHARMA GMBH and CO. KGAA
Patent: US2005/288284 A1, 2005 ;
