1-Cbz-3-乙基哌啶-3-羧酸合成路线 （共 1 条）
反应条件
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -20 - -10 °C / Inert atmosphere 1.2: -20 - 20 °C / Inert atmosphere 2.1: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere 3.1: sodium hydroxide / methanol; water / 72 h / Inert atmosphere; Reflux 3.2: Inert atmosphere; Acidic conditions View Scheme
参考文献
Nishio, Yukihiro; Kimura, Hidenori; Sawada, Naoyuki; Sugaru, Eiji; Horiguchi, Masakuni; Ono, Michiko; Furuta, Yudai; Sakai, Mutsuko; Masui, Yumi; Otani, Misato; Hashizuka, Takahiko; Honda, Yayoi; Deguchi, Jiro; Nakagawa, Tsutomu; Nakahira, Hiroyuki
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5490 - 5499
