2-氨基-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)吡啶-3-甲腈合成路线 （共 2 条）
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate in 1,4-dioxane T=100°C; 2 h; Inert atmosphere;
参考文献
OTSUKA PHARMACEUTICAL CO., LTD.; ABUDUSAIMI, Mamuti; YE, Fangguo; SUN, Jiangqin; MIYAMOTO, Hisashi; CHENG, Jay-Fei; OKA, Daisuke
Patent: WO2013/29548 A1, 2013 ;
Location in patent: Page/Page column 87 ;
反应条件
1: bromine; sodium carbonate / acetic acid / 0.83 h / 20 °C 2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate / 1,4-dioxane / 2 h / 100 °C / |Inert atmosphere View Scheme
参考文献
OTSUKA PHARMACEUTICAL CO., LTD.; ABUDUSAIMI, Mamuti; YE, Fangguo; SUN, Jiangqin; MIYAMOTO, Hisashi; CHENG, Jay-Fei; OKA, Daisuke
Patent: WO2013/29548 A1, 2013 ;
