5,6-二氢-4H-吡咯并[3,2,1-ij]喹啉-1-羧酸合成路线 (共 4 条)
反应条件
sodium hydroxide in ethanol 2 h; Heating;
参考文献
Van Wijngaarden; Hamminga; Van Hes; Standaar; Tipker; Tulp; Mol; Olivier; De Jonge
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3693 - 3699
反应条件
1: tetrahydrofuran / 24 h / Ambient temperature 2: MgCl2 / 2-methoxy-ethanol; tetrahydrofuran / 6 h / 125 °C 3: 94 percent / aq. NaOH / ethanol / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 23 p. 3693 - 3699
反应条件
1: MgCl2 / 2-methoxy-ethanol; tetrahydrofuran / 6 h / 125 °C 2: 94 percent / aq. NaOH / ethanol / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 23 p. 3693 - 3699
反应条件
quinoline; copper (II) chromite T=185°C; 3 h;
参考文献
Van Wijngaarden; Hamminga; Van Hes; Standaar; Tipker; Tulp; Mol; Olivier; De Jonge
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3693 - 3699