反应条件
1: 98 percent / pyridine / 1.) 0 deg C, 5 min, 2.) r.t., 25 h 2: 1.) Mg, I2; n-Bu3SnCl, 2.) Pd(PPh3)2Cl2, LiCl / 1.) THF, reflux, 30 min; THF, reflux, 20 h, 2.) DMF, 98 deg C, 24 h 3: 1.) NaN3, n-Bu3SnCl, 2.) NaOH / 1.) toluene, 115 deg C, 70 h, 2.) toluene, r.t., 3 h 4: NBS, AIBN / CCl4 / 3 h / Heating View Scheme
参考文献
Farmaco, , vol. 52, # 3 p. 147 - 155
