1: 1.) copper(I)iodide, methyllithium 2: 1.) 2,6-di-tertbutyl-4-methyl phenol, 2.) sulfuric acid / 1.) toluene, 95 deg C, 20 h, 2.) ethanol, 50 deg C, 24 h 3: 87 percent Chromat. / H2, NaOAc / 10percent palladium on carbon / methanol / 14 h View Scheme

Multi-step reaction with 2 steps 1: 1.) copper(I)iodide, methyllithium2: 1.) 2,6-di-tertbutyl-4-methyl phenol, 2.) sulfuric acid / 1.) toluene, 95 deg C, 20 h, 2.) ethanol, 50 deg C, 24 h