2-[3-(二异丙胺基)-1-苯丙基l]-4-甲基苯酚合成路线 （共 23 条）
反应条件
1.1: triethylamine / dichloromethane / 3 h / 0 - 10 °C / Inert atmosphere 2.1: sodium iodide / acetonitrile / 4 h / 100 °C / Autoclave 2.2: Inert atmosphere 3.1: boron tribromide / dichloromethane / Inert atmosphere 3.2: 0.5 h / 30 - 35 °C View Scheme
反应条件
1.1: potassium carbonate / methanol / 10 h / 55 - 60 °C 2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 3 h / -5 - 5 °C / Inert atmosphere 3.1: triethylamine / dichloromethane / 3 h / 0 - 10 °C / Inert atmosphere 4.1: sodium iodide / acetonitrile / 4 h / 100 °C / Autoclave 4.2: Inert atmosphere 5.1: boron tribromide / dichloromethane / Inert atmosphere 5.2: 0.5 h / 30 - 35 °C View Scheme
反应条件
in ethanol T=60 - 85°C;
参考文献
ALEMBIC LIMITED; PONNAIAH, Ravi; DESAI, Sanjay; SHAH, Chankrakant Chunilal; PATEL, Kalpesh Shantibhai; PAREKH, Viral Maheshbhai
Patent: WO2010/46801 A2, 2010 ;
Location in patent: Page/Page column 19-20; 10 ;
