1: 1) butyllithium / 1) hexanes, THF, r.t., 20 min., 2) THF, 30 min. 2: 86 percent / KOH / methanol / 16 h / Ambient temperature 3: 1) NaHCO3, 2) I2 / 1) CH3CN, 0 deg C, 5 min., 2) 0 deg C, 3 h 5: 87 percent / 40percent aq. HF / acetonitrile / 7 h / 0 °C 6: 92 percent / phosphoryl trichloride, pyridine / 5 h / 65 °C View Scheme