3-(3,5-二甲氧基-苯基)-丙醛合成路线 （共 3 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-60 - 20°C; Oxidation; 2.3 h;
参考文献
Huffman, John W.; Liddle, John; Duncan Jr., Sammy G.; Yu, Shu; Martin, Billy R.; Wiley, Jenny L.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2383 - 2396
反应条件
1: 100 percent / hydrogen / 10 percent Pd/C / ethyl acetate / 4 h / 20 °C 2: 97 percent / lithium aluminum hydride / tetrahydrofuran / 2.5 h / 0 °C 3: 93 percent / Dess-Martin periodinane / CH2Cl2; H2O / 1 h / 20 °C View Scheme
参考文献
Nikas, Spyros P.; Thakur, Ganesh A.; Makriyannis, Alexandros
Synthetic Communications, 2002 , vol. 32, # 11 p. 1751 - 1756
反应条件
1.1: magnesium turnings / diethyl ether 1.2: 88 percent / CeCl3 / tetrahydrofuran; diethyl ether / -78 - 20 °C 2.1: triethylamine / tetrahydrofuran 3.1: lithium triethylborohydride / tetrahydrofuran / 0 °C View Scheme
参考文献
Nikas, Spyros P.; Thakur, Ganesh A.; Makriyannis, Alexandros
Journal of Labelled Compounds and Radiopharmaceuticals, 2002 , vol. 45, # 12 p. 1065 - 1076
