1: 5-chlorothiophene-2-carboxamide With lithium hexamethyldisilazane in tetrahydrofuran T=20°C; 2: methyl N-((R)-2,3-epoxy-1-propyl)-N-[4-(3-oxo-4-morpholinyl)phenyl]carbamate in tetrahydrofuran 3 h; Reflux; Product distribution / selectivity;