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63148-62-9
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二甲基亚砜
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471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
125287-06-1
合成路线
（共 8 条）
14050-42-1
→
反应条件
559-70-6
β-香树精
+
125287-06-1
反应条件
Triton X-100 in phosphate buffer T=23°C; 48 h;
参考文献
Kolesnikova, Mariya D.; Wilson, William K.; Lynch, David A.; Obermeyer, Allie C.; Matsuda, Seiichi P. T.
Organic Letters, 2007 , vol. 9, # 25 p. 5223 - 5226
14050-42-1
→
反应条件
反应条件
citrate buffer; ΔGly600 mutated squalene-hopene cyclase expressed in E.coli; Triton X-100 T=45°C; pH=6.0; 16 h; Enzymatic reaction; Further byproducts given;
参考文献
Hoshino, Tsutomu; Shimizu, Kunio; Sato, Tsutomu
Angewandte Chemie - International Edition, 2004 , vol. 43, # 48 p. 6700 - 6703
54910-48-4
→
反应条件
反应条件
cell-free homogenate of E. coli after SHC D377C expression; citric acid in water T=60°C; Cyclization; addition; pH=6.0; Enzymatic reaction;
参考文献
Sato, Tsutomu; Hoshino, Tsutomu
Bioscience, Biotechnology and Biochemistry, 1999 , vol. 63, # 12 p. 2189 - 2198
14050-42-1
→
反应条件
反应条件
lanosterol synthase mutant SceErg7 Tyr510His in water T=20°C; pH=6.2; 24 h; Product distribution; Further Variations:Reagents;
参考文献
Lodeiro, Silvia; Wilson, William K.; Shan, Hui; Matsuda, Seiichi P. T.
Organic Letters, 2006 , vol. 8, # 3 p. 439 - 442
54910-48-4
→
反应条件
反应条件
citrate buffer; ΔGly600 mutated squalene-hopene cyclase expressed in E.coli; Triton X-100 T=60°C; pH=6.0; 1.5 h; Enzymatic reaction; Product distribution; Further Variations:ReagentsTemperatures;
参考文献
Hoshino, Tsutomu; Shimizu, Kunio; Sato, Tsutomu
Angewandte Chemie - International Edition, 2004 , vol. 43, # 48 p. 6700 - 6703
14050-42-1
→
反应条件
79-63-0
羊毛甾醇
+
125287-06-1
反应条件
S. cerevisiae lanosterol synthase Val454Gly mutant T=20°C; Cyclization; pH=6.2; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Joubert; Hua; Matsuda
Organic letters, 2000 , vol. 2, # 3 p. 339 - 341
14050-42-1
→
反应条件
514-45-4
帕克醇
+
79-63-0
羊毛甾醇
+
125287-06-1
反应条件
Arabidopsis thaliana cycloartenol synthase Ile481Gly; Triton X-100 in phosphate buffer Cyclization; pH=6.4; 24 h; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Matsuda; Darr; Hart; Herrera; McCann; Meyer; Pang; Schepmann
Organic letters, 2000 , vol. 2, # 15 p. 2261 - 2263
54910-48-4
→
反应条件
79-63-0
羊毛甾醇
+
125287-06-1
反应条件
cycloartenol synthase AtCAS1 Tyr410Cys mutant Product distribution; Further Variations:Reagents;
参考文献
Meyer, Michelle M.; Xu, Ran; Matsuda, Seiichi P. T.
Organic Letters, 2002 , vol. 4, # 8 p. 1395 - 1398
