反应条件
1: N-[bis(4-methoxyphenyl)methylidene]-1-(2-phenylquinolin-7-yl)methanamine With sodium hexamethyldisilazane in tetrahydrofuran
T=-5°C; 0.333333 h; Inert atmosphere;
2: 2,3-Dichloropyrazine in tetrahydrofuran
0.333333 h; Product distribution / selectivity;
参考文献
OSI PHARMACEUTICALS, INC.; MAO, Yunyu; MULVIHILL, Kristen, Michelle; RECHKA, Josef, A.; TAVARES-GRECO, Paula, A.
Patent: WO2010/123792 A1, 2010 ;
Location in patent: Page/Page column 9 ;