bromine; acetic acid 2 h;

暂无反应条件数据

in dichloromethane T=0 - 20°C; 16.5 h;

暂无反应条件数据

1.1: potassium permanganate; magnesium sulfate / water / 5.5 h / |Reflux 2.1: sodium hydroxide; water / 4 h / |Reflux 3.1: pyridine / dichloromethane; acetonitrile / 3.5 h / 45 °C / |Inert atmosphere 4.1: sodium hydride / N,N-dimethyl-formamide / 0.75 h / |Inert atmosphere; |Cooling with ice 4.2: |Inert atmosphere 5.1: sodium hydride / 6.5 h / 20 °C / |Inert atmosphere 6.1: potassium tert-butylate / diethyl ether / 2 h / 40 - 45 °C / |Inert atmosphere 7.1: tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate / water; dichloromethane / 20 °C 8.1: tetrakis(triphenylphosphine) palladium(0); morpholine / tetrahydrofuran / 20 °C 9.1: potassium carbonate; silver(I) acetate / 0.33 h / 90 - 100 °C 10.1: sodium methylate / methanol / 20 °C View Scheme

1: magnesium sulphate heptahydrate; potassium permanganate / water / 3 h / |Reflux 2: sodium hydroxide / water / 5 h / |Reflux View Scheme

1: With sulfuric acid; water 3 h; Heating / reflux; 2: With sodium hydroxide in water T=20°C;

1.1: magnesium sulphate heptahydrate; potassium permanganate / water / 3 h / |Reflux 2.1: sodium hydroxide / water / 5 h / |Reflux 3.1: pyridine / dichloromethane; acetonitrile / 3 h / 50 °C 4.1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 0.75 h / |Cooling with ice 4.2: 5 h / 20 °C 5.1: sodium hydride / paraffin oil / 6.5 h / 20 °C 6.1: potassium tert-butylate / diethyl ether / 2 h / 40 - 45 °C / |Inert atmosphere 7.1: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / water; dichloromethane / 5 h / 20 °C 8.1: morpholine; tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 18 h / 20 °C / |Inert atmosphere; |Darkness 8.2: 0.3 h / 90 - 100 °C / |Inert atmosphere; |Darkness 9.1: sodium methylate; methanol / 1 h / 20 °C View Scheme

potassium permanganate; magnesium sulphate heptahydrate in water 3 h; Reflux;

1: 67 percent / dimethylformamide / 4 h / 150 °C 2: 95 percent / conc. HCl; EtOH / 0.5 h / Heating 3: 39 percent / CuI; tert-butylnitrite / acetonitrile / 3 h / 65 °C View Scheme