1: sodium periodate 2: 53 percent / PhSNa View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 89 percent / 1,4-diazabicyclo&lt;2.2.2&gt;octane, n-butyllithium / tetrahydrofuran; hexane / 0 degC for 15 min and room t. for 1.5 h, then 0 degC, 1 h, room t., 1 h<br />2: 91 percent / p-toluenesulfonic acid / benzene / 7 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 90 percent<br />2: 100 percent / TsOH / benzene / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 89 percent / 1,4-diazabicyclo&lt;2.2.2&gt;octane, n-butyllithium / tetrahydrofuran; hexane / 0 degC for 15 min and room t. for 1.5 h, then 0 degC, 1 h, room t., 1 h<br />2: 91 percent / p-toluenesulfonic acid / benzene / 7 h / Heating<br /> <br /> &nbsp;