1.1: CHIRALPAK AD-H column / n-heptane; ethanol / Resolution of racemate 2.1: triethylamine / dichloromethane / 4 h / 20 °C / Cooling with ice 3.1: caesium carbonate / acetonitrile / 60 °C / Inert atmosphere 4.1: acetyl chloride; methanol / 4 h / 20 °C / Inert atmosphere; Cooling with ice 4.2: 0.5 h / 20 °C View Scheme

CHIRALPAK.(R). AD-H column in ethanol; n-heptane Resolution of racemate;