1-[3-(羟基甲基)苯基]乙酮合成路线 (共 4 条)
反应条件
1: With sodium tris(acetoxy)borohydride in toluene T=80°C; 4 h; 2: With sodium hydroxide in water; toluene
参考文献
Cano, Israel; Chapman, Andrew M.; Urakawa, Atsushi; Van Leeuwen, Piet W. N. M.
Journal of the American Chemical Society, 2014 , vol. 136, # 6 p. 2520 - 2528
反应条件
1: With methyl diphenyl silane; [Rh(Phebox-ph)] in toluene T=80°C; 1 h; Inert atmosphere; 2: With hydrogenchloride; water in toluene T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Shiomi, Takushi; Adachi, Takahiro; Ito, Jun-Ichi; Nishiyama, Hisao
Organic Letters, 2009 , vol. 11, # 4 p. 1011 - 1014
参考文献
OSURF (OHIO STATE UNIVERSITY RESEARCH FOUNDATION); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
Patent: WO2008/11072 A2, 2008 ;
Location in patent: Page/Page column 141; Sheet 11 ;
反应条件
glucose dehydrogenase; β-D-glucopyranose; beta-nicotinamide adeninedinucleotide phosphatedisodium salt; catalase from Micrococcus lysodeikticus; cytochrome P450 BM3 monooxygenase from Bacillus megaterium F87A, L188C double mutant; potassium chloride; oxygen; tris(hydroxymethyl)methylamine hydrochloride in aq. phosphate buffer; dimethyl sulfoxide T=30°C; pH=7.5; 24 h; Green chemistryEnzymatic reaction; Reagent/catalyst; regioselective reaction;
参考文献
Neufeld, Katharina; Marienhagen, Jan; Schwaneberg, Ulrich; Pietruszka, Joerg
Green Chemistry, 2013 , vol. 15, # 9 p. 2408 - 2421