(R)-4-氯-1,3-丁二醇合成路线 （共 3 条）
反应条件
1: With sodium tetrahydroborate in methanol; toluene T=20°C; 12 h; 2: With hydrogenchloride; water in methanol; toluene T=10°C;
参考文献
WO2008/93955 A1, ;
Paragraph 63-64 ;
反应条件
sodium tetrahydroborate in tetrahydrofuran 1 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Liebigs Annales, , # 9 p. 1877 - 1879
反应条件
hydrogenchloride; sodium hydroxide in methanol; water
参考文献
Takasago International Corporation
Patent: US5780649 A1, 1998 ;
