1-Boc-5-甲氧基吲哚-3-硼酸频那醇酯合成路线 （共 4 条）
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in dimethyl sulfoxide T=80°C; Inert atmosphere;
参考文献
ABBOTT LABORATORIES
Patent: US2011/281842 A1, 2011 ;
Location in patent: Page/Page column 62-63 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); triethylamine in 1,4-dioxane T=80°C; Masuda borylation reaction; 3 h; Inert atmosphere;
参考文献
Tasch, Boris O. A.; Antovic, Dragutin; Merkul, Eugen; Mueller, Thomas J. J.
European Journal of Organic Chemistry, 2013 , # 21 p. 4564 - 4569
反应条件
1: iodine; potassium hydroxide / N,N-dimethyl-formamide / 0.75 h / 20 °C 2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.5 h / 20 °C 3: tetrakis(triphenylphosphine) palladium(0); triethylamine / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere View Scheme
参考文献
Tasch, Boris O. A.; Antovic, Dragutin; Merkul, Eugen; Mueller, Thomas J. J.
European Journal of Organic Chemistry, 2013 , # 21 p. 4564 - 4569
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.5 h / 20 °C 2: tetrakis(triphenylphosphine) palladium(0); triethylamine / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere View Scheme
参考文献
Tasch, Boris O. A.; Merkul, Eugen; Mueller, Thomas J. J.
European Journal of Organic Chemistry, 2011 , # 24 p. 4532 - 4535
