(S)-4-苯基-2-羟基丁酸乙酯合成路线 （共 35 条）
反应条件
D-glucose T=30°C; pH=7.0; 12 h; aq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 350, # 3 p. 426 - 430
反应条件
lt;RhTFAlt;Cygt;(AMPP)gt;2; hydrogen in toluene T=20°C; P=38000 Torr; 1.5 h; other glyoxalic acid derivatives, other rhodium catalysts; var. time and pressure; Product distribution;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 7 p. 1083 - 1099
反应条件
1: (2S)-2-hydroxy-4-oxo-4-phenyl-butyric acid ethyl ester With hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol T=25°C; P=825.066 Torr; 11.5 h; 2: ethanol With hydrogenchloride T=20°C; 24 h;
参考文献
Synthesis, , # 11 p. 1679 - 1682
反应条件
hydrogen; chiral Ru complex T=20°C; P=25857.4 Torr; 72 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 128, # 17 p. 5955 - 5965
反应条件
sulfuric acid 2 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 11 p. 1583 - 1587
反应条件
Candida parapsilopsis ATCC 7330 in ethanol; water T=25°C; 1 h; Enzymatic reaction;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 14 p. 1461 - 1464
反应条件
5 palladium on charcoal; sodium acetate in ethanol T=20°C; 2 h; Inert atmosphere;
参考文献
Organic Process Research and Development, , vol. 10, # 3 p. 611 - 617
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol T=25°C; P=825.066 Torr; 11.5 h; Title compound not separated from byproducts;
参考文献
Synthesis, , # 11 p. 1679 - 1682
反应条件
hydrogenchloride; [NH2Me2]+[{RuCl[(S)-SunPhos]}2(μ-Cl3)]; hydrogen in ethanol; water T=70°C; P=10501.1 Torr; 12 h; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 73, # 18 p. 7209 - 7212
反应条件
hydrogenchloride; [NH2Me2]+[{RuCl[(S)-SunPhos]}2(μ-Cl3)]; hydrogen in ethanol; water T=30°C; P=10501.1 Torr; 12 h; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 73, # 18 p. 7209 - 7212
