(R)-(-)-2-溴-1-(对硝基苯基)乙醇合成路线 （共 13 条）
反应条件
C31H33ClN2O8RhS3(2-)*2Na(1+); sodium formate in water
T=40°C; 1 h; Inert atmosphere; enantioselective reaction;
参考文献
Li, Jiahong; Li, Xuefeng; Ma, Yaping; Wu, Jiashou; Wang, Fei; Xiang, Jing; Zhu, Jin; Wang, Qiwei; Deng, Jingen
RSC Advances, 2013 , vol. 3, # 6 p. 1825 - 1834
反应条件
borane-THF; trimethylboroxine; (1S,2R)-1-aminoindan-2-ol in tetrahydrofuran; toluene
T=-20°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Hong, Yaping; Gao, Yun; Nie, Xiaoyi; Zepp, Charles M.
Tetrahedron Letters, 1994 , vol. 35, # 36 p. 6631 - 6634
反应条件
sodium formate; N-hexadecyl-N,N,N-trimethylammonium bromide; sodium lauryl sulfate; (R,R)-TsDPEN; [{(η5-C5Me5)RhCl}2(μ-Cl)2] in water
T=28°C; 3 h; Title compound not separated from byproducts;
参考文献
Wang, Fei; Liu, Hui; Cun, Linfeng; Zhu, Jin; Deng, Jingen; Jiang, Yaozhong
Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9424 - 9429
反应条件
lipase PS-C-II in toluene
T=28°C; 48 h;
参考文献
Kapoor, Munish; Anand, Naveen; Ahmad, Khursheed; Koul, Surrinder; Chimni, Swapandeep S.; Taneja, Subhash C.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2005 , vol. 16, # 3 p. 717 - 725
反应条件
sodium hydroxide; sodium phosphate buffer; Candida rugosa lipase in ethylene glycol dimethyl ether; water
T=28°C; pH=7; 2 h; Title compound not separated from byproducts;
参考文献
Kapoor, Munish; Anand, Naveen; Ahmad, Khursheed; Koul, Surrinder; Chimni, Swapandeep S.; Taneja, Subhash C.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2005 , vol. 16, # 3 p. 717 - 725
反应条件
Thermoanaerobacter alcohol dehydrogenase in hexane; isopropyl alcohol
T=30°C; pH=7; 18 h; Tris-SO4 bufferEnzymatic reaction; optical yield given as percent eechemoselective reaction;
参考文献
Bisogno, Fabricio R.; Cuetos, Anibal; Orden, Alejandro A.; Kurina-Sanz, Marcela; Lavandera, Ivan; Gotor, Vicente
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 10 p. 1657 - 1661
反应条件
1: With sodium tetrahydroborate in methanol
3 h;
2: With Chiralpak AS column in hexane; isopropyl alcohol
参考文献
Lutje Spelberg, Jeffrey H.; Tang, Lixia; Van Gelder, Marc; Kellogg, Richard M.; Janssen, Dick B.
Tetrahedron Asymmetry, 2002 , vol. 13, # 10 p. 1083 - 1089
反应条件
1: 70 percent / bromine; acetic acid
2: Saccharamyces cerevisiae / 24 h
View Scheme
参考文献
Kapoor, Munish; Anand, Naveen; Ahmad, Khursheed; Koul, Surrinder; Chimni, Swapandeep S.; Taneja, Subhash C.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2005 , vol. 16, # 3 p. 717 - 725
反应条件
halohydrin dehalogenase from Agrobacterium radiobacter AD1; sodium bromide
Equilibrium constant;
参考文献
Spelberg, Jeffrey H. Lutje; Van Vlieg, Johan E. T. Hylckama; Tang, Lixia; Janssen, Dick B.; Kellogg, Richard M.
Organic Letters, 2001 , vol. 3, # 1 p. 41 - 43
反应条件
in methanol
T=35°C; 2 h; sonication;
参考文献
Kapoor, Munish; Anand, Naveen; Ahmad, Khursheed; Koul, Surrinder; Chimni, Swapandeep S.; Taneja, Subhash C.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2005 , vol. 16, # 3 p. 717 - 725
