hydrogenchloride; lauryl mercaptan in toluene T=45 - 50°C; 22.5 h; Inert atmosphere;

1: sodium hydroxide; water / toluene; methanol / 2 h / 50 °C 2: hydrogenchloride; lauryl mercaptan / toluene / 21 h / 40 - 45 °C / Inert atmosphere View Scheme

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '605303', constants.ctx, '0')">acetyl chloride</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11323438', constants.ctx, '0')">AlCl₃, aluminium chloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=5&deg;C;&nbsp;1&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1870517', constants.ctx, '0')">2-(4-hydroxy-phenyl)-2-phenyl-propane</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=5 - 20&deg;C;&nbsp;Friedel Crafts Acylation;&nbsp;5&nbsp;h;&nbsp;<br />Stage #3: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=30&deg;C;&nbsp;1&nbsp;h;&nbsp;<br /> <br /> &nbsp;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '385737', constants.ctx, '0')">acetic anhydride</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11323438', constants.ctx, '0')">AlCl₃, aluminium chloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=5&deg;C;&nbsp;1&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1870517', constants.ctx, '0')">2-(4-hydroxy-phenyl)-2-phenyl-propane</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=5&deg;C;&nbsp;Friedel Crafts Acylation;&nbsp;5&nbsp;h;&nbsp;<br />Stage #3: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=50&deg;C;&nbsp;1&nbsp;h;&nbsp;<br /> <br /> &nbsp;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '385737', constants.ctx, '0')">acetic anhydride</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11323438', constants.ctx, '0')">AlCl₃, aluminium chloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=5 - 10&deg;C;&nbsp;1.5&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '2118310', constants.ctx, '0')">4-(1-methyl-1-phenylethyl)phenyl acetate</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=5 - 10&deg;C;&nbsp;Friedel Crafts Acylation;&nbsp;4.5&nbsp;h;&nbsp;<br />Stage #3: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=30&deg;C;&nbsp;0.5&nbsp;h;&nbsp;<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: phosphoric acid / 4 h / 90 - 95 &deg;C / Inert atmosphere<br />2.1: AlCl₃, aluminium chloride / dichloromethane / 1.5 h / 5 - 10 &deg;C / Inert atmosphere<br />2.2: 4.5 h / 5 - 10 &deg;C<br />2.3: 0.5 h / 30 &deg;C<br /> <br /> &nbsp;