4-磺基-2,3,5,6-四氟苯甲酸合成路线 （共 5 条）
反应条件
hydrogenchloride; sodium hydroxide; NaSH; dihydrogen peroxide in water; acetic acid
参考文献
Imperial Chemical Industries PLC
Patent: US5169983 A1, 1992 ;
反应条件
dihydrogen peroxide; acetic acid T=70°C; 2 h;
参考文献
Fielding, H. C.; Shirley, I. M.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 1 p. 15 - 31
反应条件
1: aq. NaOH, NaHS / 2 h / 70 °C 2: 978 mg / 30percent H2O2, AcOH / 2 h / 70 °C View Scheme
参考文献
Fielding, H. C.; Shirley, I. M.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 1 p. 15 - 31
反应条件
thionyl chloride; N,N-dimethyl-formamide 6 h; Heating; Yield given;
参考文献
Fielding, H. C.; Shirley, I. M.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 1 p. 15 - 31
反应条件
1: SOCl2, DMF / 6 h / Heating
2: NaF, Ph4PBr / various solvent(s) / 10 h / 155 °C
3: diethyl ether
View Scheme
参考文献
Fielding, H. C.; Shirley, I. M.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 1 p. 15 - 31
