2-甲基-2-(5-硝基-2-吡啶)丙腈合成路线 （共 3 条）
反应条件
potassium carbonate in acetonitrile T=20 - 40°C;
参考文献
HUTCHISON MEDIPHARMA LIMITED; SU, Weiguo; ZHANG, Weihan; YANG, Haibin
Patent: WO2012/34526 A1, 2012 ;
Location in patent: Page/Page column 31 ;
WO 2012/034526 A1
反应条件
potassium carbonate T=20 - 40°C;
参考文献
Su, Weiguo; Zhang, Weihan; Yang, Haibin
Patent: US2013/190307 A1, 2013 ;
Location in patent: Paragraph 0146; 0149 ;
反应条件
1: With SnCl2·2H2O in ethyl acetate 4 h; Reflux; 2: With sodium hydroxide in water; ethyl acetate T=20°C; pH=8 - 9;
参考文献
Su, Weiguo; Zhang, Weihan; Yang, Haibin
Patent: US2013/190307 A1, 2013 ;
Location in patent: Paragraph 0146; 0150 ;
