5-[4-(氨基甲基)-3,5-二甲氧基苯氧基]戊酸乙酸酯合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in acetic acid T=25°C; P=2280 Torr; 2 h;
参考文献
Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany
Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743
反应条件
1: 1.) KOtBu / 1.) DMF, 25 deg C, 2.) 110 deg C, 5h 2: 4N aq. NaOH / methanol / 1 h / 25 °C 3: 95 percent / NH2OH, Na2CO3 / H2O / 2 h 4: 96 percent / H2 / 10percent Pd/C / aq. acetic acid / 2 h / 25 °C / 2280 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 12 p. 3730 - 3743
反应条件
1: 1.) KOtBu / 1.) DMF, 25 deg C, 2.) 110 deg C, 5h 2: 4N aq. NaOH / methanol / 1 h / 25 °C 3: 95 percent / NH2OH, Na2CO3 / H2O / 2 h 4: 96 percent / H2 / 10percent Pd/C / aq. acetic acid / 2 h / 25 °C / 2280 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 12 p. 3730 - 3743
反应条件
1: 95 percent / NH2OH, Na2CO3 / H2O / 2 h 2: 96 percent / H2 / 10percent Pd/C / aq. acetic acid / 2 h / 25 °C / 2280 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 12 p. 3730 - 3743
反应条件
1: 4N aq. NaOH / methanol / 1 h / 25 °C 2: 95 percent / NH2OH, Na2CO3 / H2O / 2 h 3: 96 percent / H2 / 10percent Pd/C / aq. acetic acid / 2 h / 25 °C / 2280 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 12 p. 3730 - 3743
反应条件
sodium carbonate in 1,4-dioxane T=25°C; 3 h; Yield given;
参考文献
Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany
Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743
反应条件
sodium carbonate in 1,4-dioxane T=25°C; 3 h;
参考文献
Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany
Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743
