反应条件
1: With sodium hydrogencarbonate in N,N-dimethyl-formamide
T=60°C; 16 h;
2: With hydrogenchloride in water; ethyl acetate; N,N-dimethyl-formamide
T=20°C; pH=3;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; NATIONAL INSTITUTES OF HEALTH; COHEN, Seth M.; AGRAWAL, Arpita; DESOTO, Jamie; POMMIER, Yves; MADDALI, Kasthuraiah
Patent: WO2012/106534 A2, 2012 ;
Location in patent: Page/Page column 70 ;
WO 2012/106534 A2
