3-[(4-氟苯甲基)氧]苯乙酸合成路线 （共 2 条）
反应条件
1: With potassium hydroxide in tetrahydrofuran; methanol; water 2 h; Heating / reflux; 2: With hydrogenchloride in tetrahydrofuran; methanol; water
参考文献
Shiseido Co., Ltd.
Patent: EP1422224 A1, 2004 ;
Location in patent: Page 21 ;
反应条件
1.1: K2CO3 / dimethylformamide / 0.5 h / 20 °C 1.2: 61 percent / dimethylformamide 2.1: 68 percent / aq. NaOH / ethanol / 20 °C View Scheme
参考文献
Rakowitz, Dietmar; Angerer, Helga; Matuszczak, Barbara
Archiv der Pharmazie, 2006 , vol. 339, # 10 p. 547 - 558
