反应条件
1: C8H7FO4 With caesium carbonate in N,N-dimethyl-formamide
T=20°C; 0.5 h;
2: ethylene dibromide in N,N-dimethyl-formamide
T=80°C; 16 h;
参考文献
Xu, Rong; Hong, Jinsoo; Morse, Cheryl L.; Pike, Victor W.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 19 p. 7035 - 7047