1: 1) KHMDS, 2) Et3N / 1) THF, -78 deg C, 60 min, 2) -78 deg C, 45 minalp 2: MCPBA / hexane / 0.5 h / Ambient temperature 3: aq. HF / acetonitrile / 0.33 h / Ambient temperature 4: NaIO4 / H2O; methanol / 1 h / Ambient temperature View Scheme

1: aq. HF / acetonitrile / 0.33 h / Ambient temperature 2: NaIO4 / H2O; methanol / 1 h / Ambient temperature View Scheme

sodium periodate in methanol; water 1 h; Ambient temperature; Yield given. Yields of byproduct given;

sodium periodate in methanol; water 1 h; Ambient temperature; Yield given. Yields of byproduct given;

sodium hydroxide in tetrahydrofuran